clinical trials

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Popular Cancer Drug Is Iffy and Expensive

Widely prescribed Avastin doesn't prolong life, studies say

(Newser) - Avastin is one of the most widely prescribed cancer drugs in the world, but it might not work, the New York Times reports. The drug, made by Genentech, brings in about $2.3 billion a year in the US alone, but recent trials have shown that though the drug shrinks...

Vets Used to Test Drugs Linked to Suicide

VA accused of treating troubled patients like 'lab rats'

(Newser) - Combat veterans suffering post-traumatic stress disorder were recruited for clinical trials of drugs linked to suicide and mental disorders, ABC reports. In a trial involving the smoking-cessation drug Chantix, the VA did not warn patients of the drug's serious potential side effects until 3 months after the FDA and the...

How Congress Can Help Ted Kennedy
How Congress Can Help
Ted Kennedy
Opinion
Jun 11, 2008 8:00 AM CDT

How Congress Can Help Ted Kennedy

New bill would give terminally ill access to unproven drugs

(Newser) - Ted Kennedy has, at best, about two years to live. A drug exists that might extend his life, but Kennedy, and legions of other cancer sufferers, won’t get it because it hasn’t been through Phase III FDA trials. But congress could yet come to the rescue; a bill...

Despite Danger, FDA Sanctioned Artificial Blood Studies

Product tripled heart attack risk in subjects

(Newser) - The Food and Drug Administration repeatedly approved experiments using artificial blood despite data showing the products to be dangerous, the Washington Post reports. Investigators from the National Institutes of Health found heart attack risk tripled and death increased by 30% for subjects in 16 studies testing five kinds of artificial...

Doc: Merck Fudged Minutes of Meeting

Vytorin probe challeges firm's account of delay in trial results

(Newser) - Merck's "minutes" of a meeting of heart doctors discussing cholesterol drug Vytorin were created a month after the meeting and distorted the viewpoints of the experts, one panel member changes. The drug company submitted the document to congressional investigators probing its two-year delay in releasing a report saying the...

Cold Virus Joins Cancer Fight

Brain tumors may yield to targeted infection

(Newser) - Scientists are trying to beat some of the most untreatable forms of cancer by employing another undefeated ailment: the common cold. A research team in Seattle has "modified the viruses so they can selectively target the tumor cells, replicate inside them and kill them," says one of the...

Firms Hid Bad News on Heart Drugs 2 Years: Doc

Merck and Schering-Plough delayed trial results on Vytorin, Zetia

(Newser) - A scientist hired by two drug companies to conduct trials of cholesterol-lowering drugs accused the firms of deliberately delaying release of the results, the New York Times reports. The results for the Vytorin and Zetia trials—which showed the drugs don't work to reduce plaque in arteries—were not released...

2 Top Cholesterol Drugs, Vytorin and Zetia, Don't Work

Cardiologists urge prescribing statins over Vytorin, Zetia

(Newser) - Two top-selling cholesterol drugs  proved in a recent study to be largely ineffective in slowing the clogging of arteries, a panel of cardiologists said yesterday. Doctors should only prescribe Vytorin and Zetia if other medications don't work, and should rely instead on statins such as Lipitor and Zocor, they said....

Scientists Build Immune System in Test Tube

Breakthrough could make it easier, and safer, to test vaccines

(Newser) - Scientists have discovered a way to produce tiny artificial human immune systems, Time reports, a breakthrough that could transform vaccine research. The process—called Modular Immune In Vitro Construct—will allow researchers to test budding medicines as never before and possibly make faster progress against AIDS and other killers. 

New Aspirin Spares Users Stomachaches

Italian scientists alter key molecule in painkiller

(Newser) - Aspirin is one of the world’s top painkillers, but it has a nasty way of attacking the stomach lining. That could soon be a thing of the past, thanks to a team of Italian researchers who have molecularly altered the drug. The new aspirin “has no side effects,...

Dutch Pharma Firm Preps Pot Pill
Dutch Pharma Firm Preps
Pot Pill
Jan 27, 2008 1:31 PM CST

Dutch Pharma Firm Preps Pot Pill

Drug may hit shelves in 5 years for migraine, Parkinson's victims

(Newser) - Why smoke pot when you can pop a pill? Echo Pharmaceuticals is jumping into Phase II trials for a new cannabis pill that could snag 20%-30% of the booming medical marijuana market, Reuters reports. The Dutch firm plans to sell the pill within 5 years, giving medical marijuana users a...

FDA Mandates Suicide Risk Assessment in Drug Trials

Danger doesn't lie only in antidepressants

(Newser) - The Food and Drug Administration is now requiring drug companies to monitor suicide warning signs in clinical trials for experimental drugs, the New York Times reports. In the wake of studies showing that antidepressants might increase the risk of self-harm in children and teens, the agency is showing an awareness...

Shots Could End Coke Addiction
Shots Could End Coke Addiction
Jan 2, 2008 8:02 AM CST

Shots Could End Coke Addiction

Vaccine stops drug from producing a high

(Newser) - Scientists have developed a potential vaccine against cocaine addiction and have asked the federal Food and Drug Administration to greenlight large-scale clinical trials. The injections of modified cocaine work by stimulating the immune system to attack cocaine when it's ingested, preventing the drug from producing a high, reports the Houston ...

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